There is market pressure for a PRP product with decreased red blood cell contamination, especially in aesthetic and cosmetic procedures and in sports medicine to reduce potential complications in joint treatment. Reduced granulocyte levels may also be desirable. While granulocytes are helpful in wound debridement and preventing infection, high granulocyte levels may be inflammatory.

This study assessed the PRP products from platforms such asEmcyte PRP in NJ,these are red cell reduction methods and have a programmable setting to control RBC level in the product. The study is a paired sample design, with each donor tested on all the PRP platforms.

The Pure PRP device produced a reduced Red Blood Cells PRP product. Only 2% of the granulocytes were retained, a reduction of 84% from the baseline whole blood values. The Pure PRPproducts had higher cell concentration and calculated cell metrics including platelet yield and concentration, RBC, mononuclear, and granulocyte cell recoveries than either the clear PRP.

The average concentrations for all growth factors measured were higher in Pure PRP products compared to others; however, The differencewas not significantly different between the Pure PRP and Clear PRP products. Both red cell reduction platforms had similar processing timesand the number of aseptic entries.